However, camphors effects on blood circulation to the skin and on thermal sensation have not. Vogt koyanagi harada syndrome vkh is a multisystemic granulomatous autoimmune disease affecting organs with high melanocyte concentrations including the eye, cns, inner ear, and skin. Vogtkoyanagiharada disease genetic and rare diseases. Animal models of vogtkoyanagiharada disease sympathetic. Vogt koyanagi harada disease can have good final outcomes if treated promptly. Touitou v, escande c, bodaghi b, cassoux n, wechsler b, lemaitre c, et al. The aims of this study were to evaluate the epidemiology of infection by sphingobacterium in a cohort of patients affected by cystic fibrosis cf, the antibiotic susceptibility and the dna fingerprinting of the isolated strains and to. Vogtkoyanagiharada vkh disease is a bilateral, chronic granulomatous panuveitis associated with central nervous system, auditory, and. Orbital mr imaging findings included bilateral choroidal and retrobulbar contrast enhancement, while brain findings included white matter abnormalities on flair and leptomeningeal enhancement. Vogtkoyanagiharada disease vkhd is a defined as a bilateral granulomatous panuveitis that affects pigmented struc tures, such as the. Vogtkoyanagiharada vkh disease is defined as a bilateral granulomatous panuveitis with or without extraocular manifestations affecting. Ed sc i561235304 a thesis is submitted in partial fulfillment of the requirements for the award of the degree of master of science in the school of pure and applied sciences of kenyatta university.
Vogt koyanagi harada syndrome vkhs is a rare multisystemic autoimmune disease that affects tissues containing melanin, including the eye, inner ear, meninges, and skin. Jan 21, 2011 figure 1771 fundus in the uveitic phase of vogt koyanagi harada disease. A u g u s t 3 1, 2 0 1 0 v o l u m e 9 n u m b e r 1 6 contemporary vogt koyanagi harada vkh syndrome is a multisystemic immune disorder characterized by. We present the clinical case reports of elderly vogtkoyanagiharada vkh disease patients, including the oldest patient at onset to date. New criteria, taking into account the multisystem nature of vogtkoyanagiharada disease, with allowance for the different ocular findings. Impact of endoscopic surgery for an uncommon liposarcoma of the posterior wall of the oropharynx. Research methodology module 3 conducting the research and examples of research at the university prof.
Vogtkoyanagiharada disease vkhd is a rare granulomatous inflammatory disease that affects pigmented structures, such as eye, inner ear. Indocyanine green angiography in vogtkoyanagiharada disease. Ishii h, trapnell bc, tazawa r, inoue y, akira m, kogure y, tomii k, takada t, hojo m, ichiwata t, goto h, nakata k. Invehicle speaker recognition using independent vector analysis. Some ethnic groups have a higher probability of developing the disease, including asians, indians and latin americans and females are affected more often. Phd in genetics, university of barcelona, barcelona, 2010. Vogtkoyanagiharada syndrome is a bilateral, chronic, diffuse granulomatous panuveitis frequently associated with neurological, auditory, and. Vogt koyanagi harada disease vkh disease is a disease that affects several parts of the body, including the eyes, ears, nervous system, and skin. Retinal pigment epithelial changes in chronic vogtkoyanagiharada disease.
Bacteria that belong to the genus sphingobacterium are gramnegative, nonfermentative bacilli, ubiquitous in nature and rarely involved in human infections. Khalid director center for ai and robotics universiti teknologi malaysia utm a 2day course at gmi 4 conducting the research 4. Sphingobacterium respiratory tract infection in patients. Key research findings 2016 research outline key findings sales of erp software package license in 2015 rose by 8. New criteria, taking into account the multisystem nature of vogt koyanagi harada disease, with allowance for the different ocular findings. Vogt koyanagi harada s syndrome is a rare disease that affects tissues containing melanocytes, such as the eyes, central nervous system, inner ear and skin. High power nb injection is reliably carried out in every 3 minutes. Yamanetanaka 2006 assumes gitksan harmony has variations across speakers. Revision to neuroscience research manuscript no 0800r role of basal ganglia brainstem pathways in the control of motor behaviors takakusaki, k. Vogt koyanagi harada disease is a rare disorder of unknown origin that affects many body systems, including as the eyes, ears, skin, and the covering of the brain and spinal cord the meninges.
List of original publications this thesis is based on the following publications. Melanocytes are specialized cells that produce a pigment called melanin. The diagnosis of vkh syndrome is clinical and confirmed by imaging. Some ethnic groups have a higher probability of developing the disease, including asians, indians and latin. Vogtkoyanagiharada disease with onset in elderly patients. Vogtkoyanagiharada syndrome vkhs is a rare multisystemic autoimmune disease that affects tissues containing melanin, including the eye, inner ear, meninges, and skin. Diagnostic and therapeutic management of vogt koyanagi harada syndrome. Minority language groups are important in this regard as they largely contribute. Association between sleep disorders, sleep duration, quality of sleep, and hypertension. A case report on vogtkoyanagiharada disease seen at a. Yano research institute november 24, 2017 research summary 2462 honcho, nakanoku, tokyo 1648620, japan global amoled market. Imaging tests helped to confirm the diagnosis of vogtkoyanagiharada vkh and evaluation of disease involvement.
We describe a 28yearold man with presumed vkh syndrome, whose presenting symptoms were bilateral impaired vision and headaches. Konsistensi niat dan perilaku berhenti merokok pada. Large helical device bl1 bl2 bl3 negativeionbased lhdnbi three injectors with six negative ion sourcesoperational in 1998 with 2 injectors, and 1 injector in 2001. Invehicle speaker recognition using independent vector. Conclusions with the exception of zno, the best tcos are high octahedral site density crystal structures they are ntype only the basis cations are in, sn, zn, cd and ga. Viscosity and solidification temperature of sio 2 caona. Read rw, yu f, accorinti m, bodaghi b, chee sp, fardeau c, et al. Vogtkoyanagiharada disease nord national organization. Trivedi abstract as part of humancentered driver assist framework for holistic multimodal sensing, we present an evaluation of independent vector analysis for speaker recognition task inside an automotive vehicle.
Ftcs red flags rule effective 2009 annual session p. Key research findings 2016 research outline key findings global thermal conductive filler market in 2015 projected to achieve 8,377 tons, forecasting market size to be 10,882 tons by 2020 the global thermal conductive filler market in 2015 reached 8,377 tons, based on the sales. Referencespulmonary alveolar proteinosisinformation on. Camphor induces cold and warm sensations with increases in. Cases four patients with vkh disease, whose ages at onset were 68 to 89 years, were treated at kochi medical school hospital between december 2002 and september 2004.
The disease is characterised by bilateral uveitis associated with a varying constellation of auditory, neurological and cutaneous manifestations. Calculation of cross sections for elastic scattering of electrons by a magnesium atom at intermediate energies by kariuki peter kinuthia b. Focal neurologic signs such as cranial nerve palsies, hemiparesis, and optic neuritis are relatively uncommon. Hubungan antara kualitas tidur dengan tekanan darah pada remaja usia 1517 tahun di sma negeri 1 tanjung morawa. The signs and symptoms of vkh disease are caused by chronic inflammation of melanocytes. Research rationale linguistic diversity is one of the main cornerstones of europes cultural heritage, which was recognized in article 22 of the charter of fundamental rights of the european union.
Increased peripheral blood cd4plus cd8plus tcell ratios have been seen in vkh, suggesting an immunemediated disease. Comparative study of highresolution ct findings between autoimmune and secondary pulmonary alveolar proteinosis. Vogtkoyanagiharadas syndrome and its multisystem involvement. Watanabe 1,9, hideo hatase 1, masato kinoshita 2, kazuyoshi omuta 3, takeharu bando 4, naoki kamezaki 5, katsufumi sato 6, yoshimasa matsuzawa 5, kiyoshi goto 7, yoshito nakashima 8, hiroshi takeshita 8, jun aoyama 1, katsumi tsukamoto 1. Request pdf animal models of vogtkoyanagiharada disease sympathetic ophthalmia we aimed to establish the animal model of vogtkoyanagiharada. Selig, dnp, aprn, rncob, cplc lori baas rubarth, phd, aprn, nnpbc submitted on december, 20 in partial fulfillment of the doctor of nursing practice degree. Vogtkoyanagiharada syndrome current perspectives abeir baltmr,1 sue lightman,1,2 oren tomkinsnetzer 1uveitis service, moorfields eye hospital, london, uk. Even though by june 1917 freundlich was already well aware that this opportunity would be unusually favorable, 11 the devastating aftermath of the war put an end to any hope for a german expedition as far afield as south america or central. Arejoindertolabrune2014 abstract labrune 2014 argues that japanese r is structurally empty. Melanin is the substance that gives skin, hair, and eyes their color. H45, a strain isolated from a high altitude atacama desert soil 3 running head. I would like to thank the dean of faculty of cultural studies, dr. Vogtkoyanagiharada disease vkh is an autoimmune disorder causing a bilateral diffuse.
Imaging tests helped to confirm the diagnosis of vogt koyanagi harada vkh and evaluation of disease involvement. It is based on research carried out in the context of a dfidfunded. Invehicle speaker recognition using independent vector analysis toshiro yamada, ashish tawari and mohan m. Vogtkoyanagiharada disease vkh and birdshot retino choroiditis brc. Research activities in the engineering discipline 4. Vkh may variably also involve the inner ear, with effects on hearing, the skin and the meninges of the central nervous system. Revised diagnostic criteria for vogtkoyanagiharada disease fail. Pachymeningeal enhancement has been described previously. Total achieved injection power is 16mw against the designed 15mw. Full text full text is available as a scanned copy of the original print version. The most noticeable symptom is a rapid loss of vision. The oilwater ow interface is the simplest model of a biomembrane, being fundamentally important for understanding energy conversions i. Pigmentary changes in the eye in the chronic and recurrent phases. Vogtkoyanagiharada disease vkh is a multisystem disease of presumed autoimmune cause that affects pigmented tissues, which have melanin.
Get a printable copy pdf file of the complete article 765k, or click on a page image below to browse page by page. It is one of the only diseases that provide repetition uveitis in association with neurological and otorhinolaryngological symptoms, as labyrinthitis. There may also be neurological signs such as severe headache, vertigo, nausea, and drowsiness. Vogt koyanagi harada syndrome vkh is a disease distinguished by a triad of uveitis, dermatologic findings, and cns involvement. Vogtkoyanagiharadas syndrome is a rare disease that affects tissues containing melanocytes, such as the eyes, central nervous system, inner ear and skin. Full texthtml download pdf 879k download meta ris compatible with endnote, reference manager, procite, refworks bib tex compatible with bibdesk, latex text. Application of camphor to the skin has been empirically thought to improve blood circulation.
Diagnostic and therapeutic management of vogtkoyanagiharada syndrome. Links to pubmed are also available for selected references. Cuebased oral feeding protocols 1 evaluation of cuebased oral feeding protocols for preterm infants in the neonatal intensive care unit nicu cindy l. Include headache 82%, meningismus 55%, fever 18%, nausea 9%, vertigo 9%, orbital pain, and. Chapter 177 vogtkoyanagiharada disease free medical. Vogtkoyanagiharada vkh syndrome is one such disease that requires imt for its optimal management, and failure to do so portends a poor prognosis 4,5. Fluorinefree mould flux has been required to reduce corrosion of continuous casters. We present the clinical case reports of elderly vogt koyanagi harada vkh disease patients, including the oldest patient at onset to date. I savinko t, lauerma a, lehtimaki s, gombert m, majuri ml, fyhrquist. Pdf editor,vogtkoyanagiharada vkh syndrome is a bilateral, diffuse, granulomatous uveitis associated with exudative retinal detachment and. Pdf on aug 1, 2014, emmett t cunningham and others published vogtkoyanagiharada disease find, read and cite all the research you need on researchgate.
Kowa company acquires proethic pharmaceowa pharmaceuticals. Lecturer department of advanced medical initiatives faculty of medical sciences papers. When a language has transguttural harmony noriko yamanetanaka university of british columbia abstract. Vogtkoyanagiharada disease vkh is a systematic autoimmune disorder that affects tissues. Neurologic manifestations of vkh typically include aseptic meningitis and headache. Impact of endoscopic surgery for an uncommon liposarcoma. Lecturer department of advanced medical initiatives. Association between vogtkoyanagiharada syndrome and hladr1 and dr4 in hispanic patients living in southern california. Vogtkoyanagiharada disease is a bilateral, chronic, diffuse granulomatous panuveitis typically characterized by. Kawamura y, nakaoka h, nakayama a, okada y, yamamoto k, higashino t, sakiyama m, shimizu t, ooyama h, ooyama k, nagase m, hidaka y, shirahama y, hosomichi k,nishida y, shimoshikiryo i, hishida a, katsuurakamano s, shimizu s, kawaguchi m. Dec 23, 2009 bacteria that belong to the genus sphingobacterium are gramnegative, nonfermentative bacilli, ubiquitous in nature and rarely involved in human infections. Vogtkoyanagiharada syndrome vkhs is a disease entity consisting of an inflammatory reac tion of the uvea, the retinal pigment epithelium and the meninges, variably accompanied by in volvement of brain substance, pathology of the cranial nerves, hair and skin changes in the form. Note the exudative detachment of the neural retina due to inflammation in the choroid. The most significant manifestation is bilateral, diffuse uveitis, which affects the eyes.
551 1276 420 1458 485 1187 1043 934 1418 904 271 495 628 1079 150 107 179 736 686 1146 833 327 646 1146 485 607 1386 229 293 168 383 439 99